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Lisa M. Madden, MD

Pediatric Hematology/Oncology

Texas Transplant Physician Group: Pediatric Blood & Marrow Stem Cell Transplant

4410 Medical Dr, Suite 550
San Antonio, TX 78229

About Lisa M. Madden, MD

During a volunteer trip to El Salvador in the 1990s, where she admitted feeling “useless” just holding a flashlight for the medical staff treating locals in a line that stretched for what seemed like miles, Dr. Lisa Madden found her purpose and decided to change career paths—from working as an analytical chemist for a large pharmaceutical company to studying medicine and eventually practicing primary care in underserved communities. Her passion for science and her time in the lab, however, steered her toward oncology instead.

“I had originally planned to go into internal medicine, but then I fell in love with pediatrics during the clinical years of medical school. At first I wasn’t sure if I could do pediatric oncology, but I was so inspired the patients and their families during an elective rotation at the end of med school, I knew I had found my home, professionally.” Then, after a month-long rotation in bone marrow transplant in residency, Dr. Madden had further honed in on her true passion. “Looking back, the transplant portion of my fellowship was the happiest time in all of my medical training,” she says, and now she practices pediatric blood and marrow stem cell transplantation.

After completing a Master of Science degree focusing on chemical physics at University of Notre Dame in Notre Dame, Indiana, Dr. Madden completed a medical degree at Michigan State University College of Human Medicine in East Lansing, Michigan. She completed her residency in pediatrics at University of Iowa Hospitals and Clinics in Iowa City, Iowa and returned to Michigan to complete her fellowship in pediatric hematology/oncology at University of Michigan in Ann Arbor.

Prior to joining Texas Transplant Physician Group and the Pediatric Blood and Marrow Stem Cell Transplant team at Methodist Children’s Hospital in San Antonio, Dr. Madden served as Assistant Professor at Washington University in St. Louis, Missouri and performed blood and marrow stem cell transplants at St. Louis Children’s Hospital.

Dr. Madden’s clinical interests include malignant indications for blood and marrow stem cell transplant, alternative stem cell sources such as cord blood and haploidentical transplant, immune and cellular therapy, and she has particular interest in working with adolescents and young adults (AYA) undergoing transplant.

She also enjoys drawing and painting, bicycling, and studies the Japanese martial art, Aikido, which she says trains people to be “peaceful warriors”.

Dr. Madden is board certified in pediatrics and pediatric hematology-oncology.


  1. Mavis, B. E., Ogle, K. S., Lovell, K. L., Madden, L. M.(2002). Medical students as standardized patients to assess interviewing skills for pain evaluation. Med Educ,36 (2), 135-40 PubMed: 11869440.
  2. Marsh, R. A., Villanueva, J., Zhang, K., Snow, A. L., Su, H. C., Madden, L., Mody, R., Kitchen, B., Marmer, D., Jordan, M. 8., Risma, K. A., Filipovich, A. H., Bleesing, J. J. (2009). A rapid flow cytometric screening test for X­ linked lymphoproliferative disease due to XIAP deficiency. Cytometry B C/in Cytom, 76 (5), 334-44. PMCID: PMC2728163 PubMed: 19288545.
  3. Marsh, R. A., Madden, L., Kitchen, B. J., Mody, R., McClimon, B., Jordan, M. 8., Bleesing, J. J.,Zhang, K., Filipovich, A. H. (2010). XIAP deficiency: a unique primary immunodeficiency best classified as X linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease. Blood, 116 (7), 1079-82. PMCID: PMC2938130 PubMed: 20489057.
  4. Rosebeck, S., Madden, L., Jin, X., Gu, S., Apel, I. J.,Appert, A., Hamoudi, R. A., Noels, H., Sagaert, X., Van Loo, P., Baens, M., Du, M. Q., Lucas, P. C., McAllister-Lucas, L. M. (2011). Cleavage of NIK by the APl2-MALT1fusion oncoprotein leads to noncanonical NF-kappaB activation. Science, 331 (6016), 468-72. PMCID: PMC3124150 PubMed: 21273489.
  5. Madden, L. M., Ngwube, A. I., Shenoy, S., Druley, T. E., Hayashi, R. J. (2014) Late Toxicity of a Novel Allogeneic Stem Cell Transplant Using Single Fraction Total Body Irradiation for Hematologic Malignancies in Children. J Pediat Hematol Oncol PubMed: 25333837 2015 Mar; 37(2):e94-e101
  6. Madden, L. M., Hayashi, R. J., Chan, K.W., Pulsipher, M. A., Douglas, D. Hale,G. A. Chaudhry, S., Haut, P. Kasow, K. A., Gilman, A. Murray, L. M., Shenoy, Long-Term Follow-Up after Reduced-Intensity Conditioning and Stem Cell Transplant for Childhood Nonmalignant Disorders. Biol. Blood and Marrow Transplant, May 6, 2016 [Epub ahead of print]
  7. Mull, J.L., Madden, L.M., Bayliss, S.J., Myelodysplastic Syndrome Occurring in a Patient with Gorlin Syndrome, Pediatr Dermatol, May 31, 2016 [Epub ahead of print].


Medical School
Michigan State University College of Human Medicine, East Lansing, MI

University of Iowa Hospitals and Clinics (Pediatrics), Iowa City, IA

Pediatric Hematology/Oncology: University of Michigan, Ann Arbor, MI

Certifications & Memberships

Board Certified in Pediatrics and Pediatric Hematology-Oncology.


Children's Oncology Group
American Society of Hematology
American Society of Pediatric Hematology/Oncology
American Society for Blood and Marrow Transplantation
American Academy of Pediatrics



Languages Spoken

English, Spanish

Procedures & Conditions


  • Pediatric bone marrow transplant
  • Pediatric stem cell transplant

Indications for Treatment:

  • Leukemias
  • Lymphomas
  • Bone and soft tissue tumors
  • Brain tumors
  • Bone marrow failure syndrome
  • Sickle cell disease, thalassemia and other red blood cell disorders
  • Histiocytic disorder
  • White blood cell disorders
  • Platelet disorders
  • Immune deficiencies, including Wiskott-Aldrich syndrome (WAS) and severe combined immune deficiency
  • Solid tumors (neuroblastoma, testicular cancer, brain tumors)


Pediatric Hematology/Oncology

Sub Specialty

Pediatric Blood and Marrow Stem Cell Transplant

Office Locations

Texas Transplant Physician Group: Pediatric Blood & Marrow Stem Cell Transplant
4410 Medical Dr
Suite 550
San Antonio, TX 78229
Phone: (210) 575-2222
Fax: (210) 575-6373